Dexmedetomidine: Sedative of Choice in Substance Abuse
نویسندگان
چکیده
منابع مشابه
Dexmedetomidine: a novel sedative-analgesic agent.
Since the first report of clonidine, an alpha2-adrenoceptor agonist, the indications for this class of drugs have continued to expand. In December 1999, dexmedetomidine was approved as the most recent agent in this group and was introduced into clinical practice as a short-term sedative (<24 hours). Alpha2-adrenoceptor agonists have several beneficial actions during the perioperative period. Th...
متن کاملDexmedetomidine hydrochloride as a long-term sedative
Dexmedetomidine undoubtedly is a useful sedative in the intensive care setting because it has a minimal effect on the respiratory system. Dexmedetomidine infusions lasting more than 24 hours have not been approved since the first approval was acquired in the US in 1999. However, in 2008, dexmedetomidine infusions for prolonged use were approved in Colombia and in the Dominican Republic, and the...
متن کاملSubstance Abuse in Aging Population
substance abuse' specially opiates and prescribed drugs are spreading among the older adults. Most of the time it begins as an attempt to medicate chronic pains, medical conditions and loneliness. In other instances, it simply is the continuation of a problem that begun in young adulthood. But scholars and specialists in both fields of Addiction and Gerontology, rather neglected this fast growi...
متن کاملPrescription Sedative Misuse and Abuse
Sedatives are widely prescribed for anxiety or insomnia and include benzodiazepines, selective benzodiazepine receptor subtype agonists (z-drugs), and barbiturates. These sedatives are controlled substances due to their potential for misuse and abuse. Misuse is often self-medication (chemical coping) of psychological symptoms in ways unauthorized by the prescriber, usually as dose escalation le...
متن کامل[Rectal dexmedetomidine in rats: evaluation of sedative and mucosal effects].
BACKGROUND AND OBJECTIVES In this study, we investigated the anesthetic and mucosal effects of the rectal application of dexmedetomidine to rats. METHODS Male Wistar albino rats weighing 250-300g were divided into four groups: Group S (n=8) was a sham group that served as a baseline for the normal basal values; Group C (n=8) consisted of rats that received the rectal application of saline alo...
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ژورنال
عنوان ژورنال: Chest
سال: 2016
ISSN: 0012-3692
DOI: 10.1016/j.chest.2016.08.238